This technology consists of a method for the simultaneous development of multiple bacterial detection assays based on a T4 bacteriophage system. A T4 reporter bacteriophage strain is used that carries ...
The wrapping of single bacteriophage-infected bacteria with a polymeric nanoscale coating preserves the vitality of the replicating phages, which led to enhanced therapeutic outcomes in mice with ...
相较于传统口服生物药,噬菌体递送系统具有独特优势。它能够 直接在肠道局部释放蛋白 ,避免系统性分布导致的脱靶效应。噬菌体与宿主菌形成动态平衡,可按需释放蛋白,减少频繁给药需求。 T4 噬菌体仅感染特定大肠杆菌,且无法侵染真核细胞 ...
Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...
Conducted by Padma Shri awardee Dr Ajay Sonkar, the study found that the river contains 1,100 types of bacteriophages—microscopic viruses that selectively target and destroy bacteria ...
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