Background: The purpose of this study is to investigate the causal effect and potential mechanisms between telomere length and abdominal aortic aneurysm (AAA). Methods: Summary statistics of telomere ...

Figure 1: Strategy for detecting inter-telomeric copying of DNA. Figure 2: Detection of plasmid tag DNA at the telomere by FISH. We confirmed the FISH data by Southern-blot analysis of integrated ...

Telomeres, as physical ends of linear chromosomes, are targets of a number of specific proteins, including primarily telomerase reverse transcriptase. Access of ...

“This is the first mouse model with truly humanized telomeres because telomerase isn’t expressed in adult tissues in this model,” said Jiyue Zhu, PhD, professor, college of pharmacy and phar ...

Researchers at Washington State University (WSU) have developed genetically engineered mice with human-like telomeres, offering a new model for studying aging and disease. The findings, published in ...

Researchers analyze the following parts of DNA to determine a person's biological age: Diet, exercise, stress, smoking, sleep, and physical environment all affect a person's telomeres and DNA ...

A woman’s risk for blood clots varied by the type of hormonal contraception used, according to a nationwide cohort study conducted in Denmark.

The definition and components of each dimension ... with the potential to alter epigenetic information (e.g., telomere length and DNA methylation) that appears to be transferable across generations.

Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and ...