Thomas Prod'homme and Scott Zamvil comment on the 'Bench to Bedside' approach, examining how recent basic research implicates the antigen-presenting cell in this disease. In our 'Bedside to Bench ...

This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

msx.upmc.edu Possible mechanisms by which liver antigen presenting cells (APC) may facilitate tolerance induction are discussed. Tolerance may be facilitated by a distinctive combination of factors, ...

Division of Neuro-Oncology, Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California.

Despite their central role, the sustained activity of Th2 cells during allergic reactions, even in the face of constant antigen exposure, has long puzzled researchers. A research team that ...

Previously our research has shown that high salt intake activates antigen-presenting cells (APCs), causing inflammation and hypertension. This pro-inflammatory response is partly driven by the ...

Group 2 ILCs express GATA3 and cytokines such as IL-4, IL-5, and IL-13, resembling Th2 cells. Group 3 ILCs, defined by the expression of RORγt and production of IL-22 and IL-17, are analogous to Th17 ...

Oct. 9, 2024 — Researchers have developed a groundbreaking cell culture platform that enables the formation of two distinct but interconnected vascular networks. Their breakthrough holds ...

Additionally, AEG-1 was found to regulate Th1/Th2 immune homeostasis, promote glycogen accumulation ... DCs constitute a distinct class of immune cells distributed across various organs. They are ...

15, 2024 — A team tests the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell ...