This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

A persistent, often progressive, lung disease, COPD results from chronic inflammation that leads to structural changes ...

Distinct immune "signatures" in patients who develop adverse events while receiving immunotherapy for cancer may help ...

Improper self-antigen recognition by DCs and T-cell initiates, through release of specific cytokines (as described above), destructive Th1 or Th2 responses. RA, for example, is characterized by an ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

that could skew differentiation toward Th2 phenotype instead of Treg cells. Foxp3 can boost Treg metabolic and proliferative fitness by means such as reducing Pde3b. We can soon expect to ...

Oct. 9, 2024 — Researchers have developed a groundbreaking cell culture platform that enables the formation of two distinct but interconnected vascular networks. Their breakthrough holds ...

15, 2024 — A team tests the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell ...

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help ...