Toll-like receptors (TLRs) are a family of pattern recognition receptors that recognize conserved structures that are associated with infection or tissue damage. Activation of TLRs promotes ...

Why we don't have a hangover treatment by now, and how scientists are trying to prevent and minimize hangovers—and the ...

Toll-like receptors (TLRs) are one of the largest and ... TLRs on the plasma membrane (TLR1, 2, 4 and 6) detect viral proteins, which are released in the extracellular environment, while endosomal ...

We aimed to evaluate whether: EGC participate in host–bacteria interaction; S100B and Toll-like receptor (TLR) signalling converge in a common pathway leading ... taken from patients undergoing ...

Isam Nasr, director of pediatric trauma at Johns Hopkins, discusses his presentation on traumatic brain injury (TBI) that took place during the 2023 American Pediatric Surgical Association annual ...

Researchers at Baylor College of Medicine, working with other institutions, have made a breakthrough in understanding how ...

MN-166 (ibudilast) appears to benefit ALS patients over up to one year of use, an interim Phase 2b/3 trial analysis suggests.

Cholesterol restriction-mediated SREBP1 activation induces noncanonical type I IFNs, including IFN-ω and minor IFN-α subsets, ...

2024年11月22日，Acta Pharmaceutica Sinica B杂志以封面文章的形式报道清华大学药学院尹航课题组最新研究成果“Targeting toll-like receptor 7 as a therapeutic development strategy for systemic lupus erythematosus” ...

We document that HFD can prolong toll-like receptor (TLR)4-induced arthritis by increasing joint monocyte migration and further remodelling the recruited cells into M1 macrophages. Consistently, we ...

1 Department of Oral and Maxillofacial Diseases, Tampere University Hospital, Tampere, Finland 2 Department of Neurosurgery, Tampere University Hospital, Tampere, Finland 3 Department of Forensic ...