The study by Aguirre-Botero et al. shows the dynamics of 3D11 anti-CSP monoclonal antibody (mAb) mediated elimination of rodent malaria Plasmodium berghei (Pb) parasites in the liver. The authors show ...
All tested drugs were first dissolved in their respective solvents and subsequently further diluted in complete culture medium to have the desired final concentration (Supplementary Table 1 and ...
ALA = Amoebic liver abscess; Eh = Entamoeba histolytica; EhCP = E. histolytica cysteine proteinase; Ehserp = E. histolytica serine proteinase; EhSTIRP = Serine threonine isoleucine-rich protein ...
This work presents valuable data demonstrating that a camelid single-domain antibody can selectively inhibit a key glycolytic enzyme in trypanosomes via an allosteric mechanism. The claim that this ...
Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa Department of Biochemistry, Genetics and Microbiology, Institute for Sustainable Malaria Control, University of Pretoria ...