Data from the ongoing Phase 2 of EO4010 demonstrate tumor target specific immune responses and objective tumor responses, including in liver mets, in patients with previously treated microsatellite ...
These peptides (T-cell epitopes ... Focusing on a limited set of antigens is also relevant to cancer vaccination in which tumour cells or lysates may contain predominantly normal self-proteins ...
BriaCell successfully identified immunogenic (i.e. immune system activating) peptides in patients treated with Bria-IMT™, a cell-based cancer vaccine, and showed Bria-IMT™'s ability to produce a ...
Interesting targets for peptide vaccination have been defined including Wilms tumor gene 1 ... For the three aforementioned antigens, more and more epitope peptides have been defined.
However, the effectiveness of these therapies depends on the distribution of cancer-associated antigens across the tumor. Tumors with uniform antigen expression respond well to ICB therapy, while ...