The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune ...

Researchers are shining a light on cancer cells' energy centers -- literally -- to damage these power sources and trigger widespread cancer cell death. In a new study, scientists combined strategies ...

Demehri, MD, Ph.D., of the Department of Dermatology and Center for Cancer Immunology at Massachusetts General Hospital, is ...

A new study suggests certain lipids, particularly omega-6 fatty acids, which are commonly found in seed oils used to make ...

Scientists have discovered that our specialized immune cells, called T cells, are what they eat -- their switch from functional to 'exhausted' depends on the switch from metabolizing acetate to ...

In addition to targeting a specific tumor protein, the treatment includes a bispecific antibody that enhances the therapeutic ...

Restoration of intracellular acetyl-CoA by supplementing growth media with acetate reengaged AICD and rescued IFN-γ production for hypoxic Hif1α-deletion T cells. Shi and colleagues then demonstrated, ...

Bria-IMT™ plus CPI produced cancer-fighting CD8+ T cells infiltration into metastatic tumors and lymphoid tissue, leading to cancer destruction - turning “Cold” tumors and lymph nodes “Hot” on ...

Researchers are shining a light on cancer cells' energy centers - literally - to damage these power sources and trigger ...

Therapeutics highlights the infiltration of cancer fighting immune cells into tumors, using leading CD8 ImmunoPET imaging ...

Eating at least two servings of cooked tomatoes—from sautéed or roasted tomatoes to tomato soup and pasta sauce—seems to be ...

A study led by Roswell Park Comprehensive Cancer Center provides new insight into the complex interactions of the ...