Summary: New research uncovers how mitophagy, the cellular recycling of damaged mitochondria, changes dynamically in the aging mammalian brain. In memory-related cells, mitophagy rises in midlife but ...
Mitophagy plays an important role in mitochondrial homeostasis. In yeast, the phosphorylation of the mitophagy receptor Atg32 by casein kinase 2 is essential for mitophagy. This phosphorylation is ...
Mitophagy, the selective removal of damaged mitochondria, is thought to be critical to maintain neuronal homeostasis. Mutations of proteins in the pathway cause neurodegenerative diseases, suggesting ...