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Dev Cell | 酒亚明研究组揭秘巨噬细胞降解细胞外基质的新机制:中间 ...
此外,利用不同极化状态THP-1巨噬细胞的结果显示,与M1型巨噬细胞相比,M2型巨噬细胞vimentin网络更加集中,伪足小体分布更加紧密,且ECM降解能力更强。通过Transwell实验和3D共培养系统,研究人员发现M2型巨噬细胞能够显著增强A549肺癌细胞的侵袭能力,而vimentin ...
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