Abnormal growth of skin cells or keratinocytes and immune system dysfunction are believed to cause psoriasis. The immune system dysfunction involves pro-inflammatory molecules such as tumor ...

Background: Psoriasis is an inflammatory skin condition where immune cells play a significant role. The importance of the cross-talk between keratinocytes and immune cells in the pathogenesis of ...

Researchers identified Janus kinase inhibitors as a promising treatment for the severe drug-induced skin condition toxic ...

A large Medicare cohort study found that the most common locations of procedurally treated keratinocyte cancers ... that patients prefer rhenium-188 skin cancer therapy (RSCT) over surgery in ...

Skin pigmentation may act as a "sponge" for some medications, potentially influencing the speed with which active drugs reach ...

Smoking is responsible for decreasing the body’s inflammatory process and immune function (due to a reduced blood flow), ...

In pemphigus vulgaris, an autoimmune disease of the epidermis, IgG autoantibodies directed against desmosomal adhesion proteins, especially desmoglein-3 and -1, cause loss of keratinocyte adhesion. We ...

In patients with primary thyroid cancer, there is an increased risk of melanoma and other non-keratinocyte skin cancers after ...

A new review has highlighted how skin tone can affect the safety and effectiveness of some medications and why the current ...

More recently, studies have investigated adhesins for human keratinocytes and their ligands ... exhibits different patterns of colonization to skin epithelial layers, which may contribute to ...