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同种异体cd33定向CAR-NKT细胞治疗骨髓驻留性髓系恶性肿瘤
研究结果 1. 原发性 AML 和 MDS 样本的生物标志物和转录组分析揭示 CAR-NKT 细胞疗法的潜力 研究人员通过对原发性 AML 和 MDS 骨髓样本进行流式细胞术和 scRNA-seq 分析,发现患者原始细胞存在不同亚群(LSCs、MPPs、CMPs 和 MBCs),且各亚群表面肿瘤抗原、NKT TCR 靶点和 ...
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