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Nature:一种新抗原疫苗在肾细胞癌患者体内成功诱导出抗癌免疫反应
这种癌症疫苗是个性化的,以识别患者体内的肾细胞癌,并以手术中切除的肿瘤组织为指导。这些作者从肿瘤细胞中提取分子特征,将其与正常细胞区分开来。这些称为新抗原(neoantigen)的分子特征是突变蛋白的微小片段,这些片段存在于肾细胞癌中,但不存在于体内 ...
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