This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

Human leukocyte immunoglobulin (Ig)-like receptors (LILR) are a family of 11 innate immunomodulatory receptors, primarily expressed on lymphoid and myeloid cells. LILRs are either activating (LILRA) ...

A successful allotransplant would depend on tolerance, which depends on each individual NK cell expressing inhibitory receptors for two completely disparate sets of MHC molecules on donor and host ...

Background/Aims: Chimeric antigen receptor (CAR) T cells for refractory or relapsed (r/r) B-cell acute lymphoblastic leukemia (ALL) patients have shown promising clinical effectiveness. However, the ...

the considerable success achieved with hu5C8 reported here strongly supports careful study of a regimen based on this antibody to prevent rejection in human allotransplant recipients. The antibody ...