Dendritic localization of the α subunit of Ca 2+ /calmodulin-dependent protein kinase II (αCaMKII) mRNA in CNS neurons requires its 3′ untranslated region (3′UTR). We investigated this ...

为探究抑郁症相关机制及寻找新靶点，安徽中医药大学 Ping Cheng 等人开展 mPFC DCC 与 CaMKII + 神经元兴奋在雄性小鼠行为绝望中作用的研究。发现二者关联及相关信号通路，为理解抑郁症发病机制和临床治疗提供新方向，值得一读。 安徽中医药大学新安医学与中药 ...

Alibaba Group Holding Limited, through its subsidiaries, provides technology infrastructure and marketing reach to help merchants, brands, retailers, and other businesses to engage with their ...

The characteristics of perforated synapses are consistent with this scenario. That CaMKII is also an essential trigger for this structural change is supported by the finding that inhibition of ...

This important chronobiological study in mice suggests that light modulated activity of Cdk5 activity on the PKA-CaMK-CREB signaling pathway provides missing molecular mechanistic details to ...

The Walt Disney Company operates as an entertainment company worldwide. It operates through three segments: Entertainment, Sports, and Experiences. The company produces and distributes film and ...

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways have been found to ...

In this valuable paper, the authors created a reporter mouse line in which the Axon Initial Segment (AIS) is intrinsically labeled by an ankyrin-G-GFP fusion protein activated by Cre recombinase, ...

Allergic rhinitis (AR) is a chronic, non-infectious condition affecting the nasal mucosa, primarily mediated mainly by IgE. Recent studies reveal that AR is intricately associated not only with type 2 ...

It’s been a minute since Lifehacker looked at the slang of Generation Z—long enough that Generation Alpha has had time to develop and spread some of its own special buzzwords and jargon.

Department of Oral Implantology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai 200001, ...