Peptides, as versatile biomolecules, continue to gain traction in various scientific fields due to their wide range of ...

研究者使用冷冻电子显微镜、AlphaFold24和基于分子动力学的改进的综合方法，在大多数区域展示了亚纳米分辨率的apoB100的结构。该结构由一个大的球状N端结构域和一个约61纳米长的连续两亲β片组成，该β片像带一样包裹着LDL颗粒。准对称分布在β带两侧的是9个战略性的链间插入物，它们延伸到脂质表面，通过远程相互作用的网络提供额外的结构支持。

As indivisible units of life, the cells of all organisms consist of four fundamental macromolecular components: nucleic acids (including DNA and RNA), proteins, lipids and glycans. From the ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

Viroporins are virally encoded transmembrane proteins that are essential for viral pathogenicity and can participate in various stages of the viral life cycle, thereby promoting viral proliferation.

State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, Beijing 100049, China ...

Butterflies represent one of the largest animal groups on Earth, yet antimicrobial peptides (AMPs) of this group are less studied in comparison with their moth counterparts. This study employed an ...

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