Traumatic brain injury (TBI), Alzheimer’s disease (AD), and epilepsy share proposed mechanisms of injury, including neuronal excitotoxicity, cascade signaling, and activation of protein biomarkers ...

Figure 2. KCC2 structure, key phosphorylation residues and regulatory domains. The KCC2 co-transporter is a ~140 kDa protein with a predicted topology of 12 membrane spanning segments, an ...