San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury. Williams didn't practice ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

Picking a D/ST in fantasy can make or break your week. Here are the ones you should target and the ones to avoid in Week 13.

The 49ers got blown out by the Packers in Week 12 and rookie wideout Ricky Pearsall was held without a catch for the second ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...