Reporting in Cancer Cell, MacDiarmid and colleagues now describe a promising new technology that firmly encapsulates chemotherapeutics into bacterial minicells, which are then guided by antibodies ...

Conventional chemotherapeutics disrupt mitotic events in proliferating cells. By exploiting the growth fraction differential between tumor cells and those of normal host tissues, tumor reduction ...

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...

Often patients with these cancers are prescribed chemotherapeutics, but sometimes this strategy stops working and scientists don't really know why. "For these patients, there aren't any good ...