Researchers from Janssen Research & Development LLC presented preclinical data for JNJ-87801493, a first-in-class CD20 targeted CD28 costimulatory bispecific antibody (Ab), currently in early clinical ...

Odronextamab monotherapy led to complete responses in all patients with previously untreated follicular lymphoma evaluable for efficacy, per ...

[100] Once the Th2 polarization process is complete, IL-4 and IL-13 promote binding of costimulatory molecules (CD40 with CD40 ligands and CD80 or CD86 with CD28) on Th2 cells and B cells ...

Activation of PRRs induces expression of several chemokines and proinflammatory cytokines, and upregulates expression of MHC class II and costimulatory molecules on both dendritic cells and ...