台湾卫生福利部桃园总医院泌尿科等多单位的研究人员 Chih-Hung Chiang、Jr-Di Yang、Wei-Lin Liu 等在《Cancer Cell International》期刊上发表了题为 ...

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Our data also indicated that RhoV induced progression and EGFR-TKI resistance of lung adenocarcinoma may be related to the activation of the AKT/ERK pathway. Conclusion: Overexpression of RhoV in lung ...

Without additional characterization of MAPK and Erk signaling, the effect of Ezrin loss remains unclear ... We considerably expanded the number of experiments to support EZRIN/EGFR/AKT network in ...

FSH activates Src which directly phosphorylates EGFR, thereby eliciting EGF-independent activation of this receptor. MAPK ERK and PI3K pathways have been shown to be activated as a result of EGFR ...

Here, we report that endosomal-localized EGFR/Ezrin complex interacts with and triggers the inhibition of the Tuberous Sclerosis Complex (TSC complex) in response to EGF stimuli. This is regulated ...

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