Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Endonuclease III (EndoIII), a key enzyme in the base excision repair (BER) pathway, ...

Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be ...

The Skin Health and Beauty Pyramid is more than a skincare routine—it’s a return to simplicity. Beautiful, healthy skin doesn ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

The drug is designed to block the CAP-dependent endonuclease (CEN) protein in the influenza virus. In preclinical studies, both in vitro and in vivo, Tivoxavir marboxil demonstrated potent ...

1 Noteworthy among the recent advancements are SHERLOCK (Specific High-sensitivity Enzymatic Reporter unlocking) 3,4 and DETECTR (DNA Endonuclease Targeted CRISPR Trans Reporter) 4. CRISPR ...

Here, the authors show that the unusual chromosome size-dependent DNA replication timing in Leishmania is influenced by RNA-DNA hybrids that are recognised by the endonuclease RNase H1.

Tivoxavir targets the CAP-dependent endonuclease (CEN) protein, a highly conserved feature in influenza viruses, making it effective against both seasonal and highly pathogenic strains of flu ...

Nanozymes are nanomaterials with intrinsic enzyme-like properties. They can specifically catalyze substrates of natural enzymes under physiological condition with similar catalytic mechanism and ...

This important study combines virology experiments and mathematical modeling to determine the nuclear export rate of each of the eight RNA segments of the influenza A virus, leading to the proposal ...