综合上述研究结果,研究人员得出结论:酒精摄入会增加食管鳞癌患者外周循环中革兰氏阴性菌的丰度,基于肿瘤细胞中 TNF 通路的上调,酒精和 LPS 协同促进食管鳞癌细胞的增殖,而 LPS 促进正常鳞状细胞的死亡,最终加速食管鳞癌的发展。这一研究成果揭示了一种全新的食管鳞癌致病机制,即酒精诱导的外周循环微生物失调和 LPS ...
Researchers evaluated demographic characteristics associated with survival trends in patients with squamous cell carcinoma of the upper esophagus.
Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings indicate that periostin, or POSTN, promotes ESCC progression by ...
The safety and short-term efficacy of neoadjuvant chemotherapy in elderly patients with resectable locally advanced esophageal squamous cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ...
Researchers from Zhengzhou University and affiliated organizations published data from a study that aimed to assess the expression levels of histone modifier enzymes in esophageal squamous cell ...
Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.
BeiGene (NASDAQ:BGNE) has received FDA approval for its drug Tevimbra in the treatment of advanced or metastatic esophageal squamous cell carcinoma, or ESCC. The drug, also known as tislelizumab ...