综合上述研究结果，研究人员得出结论：酒精摄入会增加食管鳞癌患者外周循环中革兰氏阴性菌的丰度，基于肿瘤细胞中 TNF 通路的上调，酒精和 LPS 协同促进食管鳞癌细胞的增殖，而 LPS 促进正常鳞状细胞的死亡，最终加速食管鳞癌的发展。这一研究成果揭示了一种全新的食管鳞癌致病机制，即酒精诱导的外周循环微生物失调和 LPS ...

Researchers evaluated demographic characteristics associated with survival trends in patients with squamous cell carcinoma of the upper esophagus.

Researchers from Zhengzhou University and affiliated organizations published data from a study that aimed to assess the expression levels of histone modifier enzymes in esophageal squamous cell ...

Esophageal atresia is a rare, congenital (present at birth) disorder of the digestive system in which the esophagus, the tube that normally carries food from the mouth to the stomach, does not connect ...

A total of 68 superficial esophageal neoplasias in 58 patients treated by endoscopic resection at the Osaka Medical Center for Cancer and Cardiovascular Diseases from May 2011 to March 2012 were ...

In conclusion, brownish epithelium on NBI is an important finding for the diagnosis of esophageal squamous neoplasias. The brownish coloration may be caused by thinning of the keratinous layer and ...

Tislelizumab is an IgG4 variant monoclonal antibody against PD-1 indicated for the treatment of unresectable, locally advanced or metastatic esophageal squamous cell carcinoma. Tislelizumab is a ...

Sintilimab with neoadjuvant chemoradiotherapy enhanced pCR rates in resectable, locally advanced esophageal squamous cell carcinoma. Adding sintilimab (Tyvyt) to neoadjuvant chemoradiotherapy (CRT) ...