Department of Vascular Surgery, The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital), Wenzhou City, Zhejiang Province 325000, China Laboratory of Wenzhou Pan-Vascular ...

Mosquito-borne flaviviruses encode exoribonuclease-resistant RNAs (xrRNAs) that fold into knot-like structures to prevent exonuclease Xrn1 digestion. To achieve high Xrn1 resistance, xrRNAs ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

近年来，免疫检查点抑制剂（ICI）在结直肠癌尤其是错配修复缺陷（dMMR）/微卫星高度不稳定（MSI-H）的患者中应用广泛，而除了 dMMR/MSI-H 外，在结直肠癌中还有一小部分人群存在非常罕见的超突变，即 POLE/POLD1 ...

Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and ...

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Humic soil samples were collected from Qingshuihe County (E 111° 0.68′, N 39° 0.92′), Hohhot City, Inner Mongolia Autonomous Region, China. We weighed 5 g of soil into 45 mL of sterile water and ...