Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...

Blood tests from children hospitalized with malaria found that nearly all were homozygous for the wild type of sickle cell allele. The few sickle cell carriers among them had the mildest cases of ...

Individuals A and B both have brown eyes, even though A is heterozygous and B is homozygous (dominant). Only people with a homozygous recessive genotype can have blue eyes as shown by individual C.

Homozygous Familial Hypercholesterolemia (HoFH) is a rare genetic disorder and most severe form of Familial Hypercholesterolemia (FH), characterized by reduced hepatic clearance and resultant ...

Half of the possible offspring have the same allele combination; AA homozygous dominant and the other half have the Aa heterozygous combination. Probability close probabilityThe extent to which ...

A real-world study in children with cystic fibrosis in the Netherlands found significant improvements in small airway function, BMI, and exacerbations after 12 months of treatment with ...