Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed ...

Slathering on sunscreen? You might be blocking more than just a tan. Find out the truth that no one is talking about.

Researchers suggest drugs that prevent cholesterol from being converted to 24-OHC might therefore be an effective treatment for Parkinson's disease.

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical ...

Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States ...

Hypoxia inducible factors (HIFs) and their regulatory hydroxylases the prolyl hydroxylase domain enzymes (PHDs) are the key mediators of the cellular response to hypoxia. HIFs are normally ...

The deficiency of 21-hydroxylase due to CYP21A2 pathogenic variants is a rather frequent disease with serious consequences, going from a real mortality risk to infertility and to milder symptoms, ...

Tryptophan hydroxylase (TPH) is the rate-limiting biosynthetic enzyme for serotonin. Previously, we reported elevated levels of TPH protein in the dorsal raphe nucleus (DRN) of depressed suicides ...