Figure 2. KCC2 structure, key phosphorylation residues and regulatory domains. The KCC2 co-transporter is a ~140 kDa protein with a predicted topology of 12 membrane spanning segments, an ...

This is an important study to reveal local circuit mechanisms in the POA that control body temperature and also highlight how neurotransmitter GABA and neuropeptide NTS from the same neurons ...

The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important ...

The K-Cl co-transporter KCC2 plays multiple roles in the physiology of central neurons and alterations of its function and/or expression are associated with several neurological conditions. By ...