Alternate uniforms lead the way in Week 12 of the NFL season.

Plagued by penalties, drops and a pair of missed red-zone opportunities, the Colts stumbled badly in a 24-6 loss to the ...

NFL Nation reporters react to all the action, answering the biggest questions coming out of each game. Here's what we learned ...

Detroit cruised to a 24-6 win over the Indianapolis Colts, thanks to the Colts offense sputtering after some early promise.

Jahmyr Gibbs rushed for 90 yards and scored two touchdowns as the visiting Detroit Lions extended their winning streak to ...

Watch all the highlights from the Detroit Lions' 24-6 Week 12 victory over the Indianapolis Colts. Watch the best plays by ...

The Detroit Lions rolled into Indianapolis and kept the impressive winning streak alive. Dan Campbell's Lions improved to ...

INDIANAPOLIS — Jahmyr Gibbs rushed for two scores and David Montgomery added a third touchdown run Sunday, leading the ...

Reigning champion Kansas City edged Carolina and Detroit ripped Indianapolis on Sunday to reach an NFL-best 10-1 while Dallas ...

The Indianapolis Colts (5-7) failed to capitalize on a day when the Houston Texans lost to the Tennessee Titans after they ...

Once again, the Detroit Lions fell behind early and then rolled to a dominating 24-6 victory over the Indianapolis Colts.

Quarterback C.J. Stroud and the Houston Texans insisted a healthy lineup and a return home would spark their ailing offense ...