The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

However, in the half-century since the structure of DNA was first elaborated ... complex can then inhibit transcription of an mRNA molecule that has a sequence complementary to its RNA component.

In particular, there is an area near the 5' end of the molecule that is known ... Begins After the Assembly of a Complex Structure The translation of mRNA begins with the formation of a complex ...

rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and catalyze the formation of peptide ... The resulting primary transcript, known as pre-mRNA in eukaryotes, ...

In DNA, two complementary strands of nucleotides pair up through hydrogen bonds between the bases (A with T and G with C) to form the iconic double helix structure. RNA is usually single-stranded ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients ...

In this study, the researchers reveal the structure of U11 snRNP—one of the five subunits of the minor spliceosome, which ...

"I find mRNA very fascinating because as an informational molecule, its function is encoded ... versatility to extensively ...

To add multiple polyA tails to the mRNA backbone and create the branched structure, the scientists used click chemistry, which is a set of reactions used for joining two molecular entities. Additional ...