Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...
This study investigates the role of macrophage lipid metabolism in the intracellular growth of Mycobacterium tuberculosis. By using a CRISPR-Cas9 gene-editing approach, the authors knocked out key ...
Indeed, the pathogen seems like ancient history — but as recent developments indicate, tuberculosis isn’t done with us yet.
Tuberculosis (TB) is a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. While multidrug treatment regimens are the standard of care, the lengthy treatment schedule and ...
1 天on MSN
Australian researchers have developed a new mRNA vaccine for tuberculosis, showing effective results in mice. The vaccine ...
Every year, 10 million people contract tuberculosis (TB), a disease caused by the bacterium Mycobacterium tuberculosis (Mtb), and approximately 1.5 million patients succumb to the disease. Treatment ...
According to the Global TB Report by WHO, India has seen a decline of 16 per cent in TB incidence (new cases emerging each ...
A simple model projected which strains were likely to be highly transmissible, with implications for public health.
Tuberculosis may seem like a historic malady, but it’s still the world’s deadliest infectious disease. Here’s what you need ...
Römpp, A., Treu, A., Kokesch-Himmelreich, J. et al. The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis. Nat Commun 16, ...
2 天
IFLScience on MSNNew mRNA Vaccine Against World's Biggest Infectious Killer Shows PromiseA new mRNA vaccine against tuberculosis (TB) is showing favorable results in preclinical trials. With only one currently ...
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