We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8) allows for renal allotransplantation in outbred, MHC-mismatched rhesus monkeys without acute rejection.

Experimental autoimmune encephalomyelitis (EAE) is a model of the neuroimmune system responding to priming with central nervous system (CNS)-restricted antigens. It is an excellent model of post ...

The study noted that the European dogs eventually outbred the Indigenous dog population. As a result, there was the maternal Indigenous dog ancestry was almost wiped out. In recent times ...

Correspondence to Professor D Gareth Evans, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, St Mary’s Hospital, University of Manchester, Manchester M13 9WL, UK; ...

Another explanation is that the variation of neutralising titres in outbred rhesus macaques can be influenced by the selective antigen presentation by varying major histocompatibility complex (MHC) in ...