A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a ...

We are investigating the molecular, cellular and physiological mechanisms underlying the dual actions of PIP2, identifying regions and amino acids that are involved in PIP2 binding and PKA ...

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Law of divorce; children blessed; rich young ruler; request of James and John; triumphal entry; cleansing the Temple. They said unto Him, Grant unto us that we may sit, one on Thy right hand, and the ...

Moreover, resveratrol’s capacity to either suppress or induce ferroptosis through the modulation of signaling pathways, including Sirt1 and Nrf2, unveils novel therapeutic avenues. Despite resveratrol ...

In addition, in the sensory neurons of higher mammals, the two peptides can activate two proteins—kinases PKA-II and ERK1/2—involved in signal transduction. The latter suggests that they are ...

This diagram shows the possible mechanism by which melatonin prevent MCAO-induced neuronal damage, synaptic deficit, and neurodegeneration through Enolase/PI3K/AKT/CRMP2 pathway. BBB, blood brain ...

The ubiquitin-proteasome system is the main proteolytic pathway for quality control (PQC) and regulatory degradation of proteins in living cells. Systolic overload, as seen in hypertension and aortic ...

Career readiness—and especially the somewhat amorphous concept of career pathways—has gained momentum over the past several years, driven by a confluence of educational and economic factors and, more ...