We discovered that Frk enhances the activation of the IFN-I production pathway by targeting TBK1. Mechanistically, Frk promotes the K63 ubiquitination of TBK1 and subsequent activation of the ...

2025 年 2 月 19 日，罗小金课题组在 Plant Biotechnology Journal 杂志上发表了题为“ OsMAPKKK5 Affects Brassinosteroid Signal Transduction via Phosphorylating OsBSK1-1 and Regulates Rice Plant Architecture and Yield” 的研究论文 ...

近日，南京农业大学生命科学学院张阿英教授团队在《 Plant Cell》上发表了题为“ The maize GSK3-like kinase ZmSK1 negatively regulates drought tolerance by phosphorylating the tranion factor ZmCPP2”的研究成果， 该研究揭示了GSK3类激酶在干旱胁迫响应中调节抗氧化防护的新机制 ...

2025年2月19日，罗小金课题组在Plant Biotechnology Journal杂志上发表了题为“OsMAPKKK5 Affects Brassinosteroid Signal Transduction via ...

Mechanotransduction refers to the processes through which cells sense and respond to mechanical stimuli by converting them to biochemical signals that elicit specific cellular responses ...

Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in the world, with a high rate of morbidity. The invasion and metastasis of ESCC is the main reason for high mortality. More ...

Researchers identified an enzyme that helps Plasmodium-infected red blood cells adhere to the placenta, providing molecular ...

Jack E Dixon as a postdoctoral fellow from 2014 to 2020. During that time his research was focused on the role of DYRK2 as a kinase phosphorylating and regulating the 26S proteasome. As a post ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

The reason for this lies in the cyclins' cooperation with a kinase. Kinases are responsible for phosphorylating amino acids in substrates -- a key process for cell division. Another important ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.