The production of ribosomes begins when RNA polymerase I (Pol I) synthesizes pre-rRNA, a precursor transcript of the mature ...

Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...

My scientific interests center on nucleases, a functionally diverse class of enzymes that catalyze the cleavage of phosphodiester bonds to support a wide breadth of pathways, including DNA replication ...