al. describes studies on assessment of key factors impacting variability in AAV vector genome titration by digital PCR. Quoting from the abstract: "Recombinant adeno-associated virus (rAAV ...

自CRISPR技术首次问世以来，已逾十年，其对生命科学与生物医学研究领域的变革性影响不容小觑。该技术显著缩短了动物模型的构建周期，为多物种新模型的开发提供了前所未有的机遇，加速并拓宽了筛选策略的应用范围，尤为重要的是，促进了针对先前难以治愈的遗传性疾 ...

LAUSANNE, Switzerland--(BUSINESS WIRE)--NewBiologix, a technology innovation company pioneering tools for efficient, cost-effective, and scalable production of viral vectors for gene and cell therapy, ...

Adeno-associated viruses (AAV) are powerful instruments in gene therapy. AAV particles comprise a protein capsid that along ...

rAAV是基因治疗中基因传递的重要媒介，不同的rAAV载体转导会受不同的宿主因子影响，了解这些机制对成功的基因治疗大有帮助。这篇论文鉴别了影响rAAV5转导的宿主因子 介绍 重组腺相关病毒（rAAV）是基因治疗中递送基因的重要载体，能转导多种细胞类型、非 ...

The genome is the full genetic complement of an organism, encoded in either DNA or, in many viruses, RNA. It includes both the genes and non-coding sequences. The most widespread chromosomal sex ...

Next-generation sequencing allows for critical insights into gene therapy products, which can help streamline and accelerate ...

Genome evolution is the process by which a genome changes in structure over time, through mutation, horizontal gene transfer, and sexual reproduction. The study of genome evolution involves ...

The immense variation in the amount of DNA contained in the cells of organisms has long fascinated scientists. Known as the genome size (GS), or C-value of a species, the amount of DNA in one entire ...

Exegenesis Bio, a clinical stage global gene therapy company is pleased to announce that US FDA has granted Orphan Drug Designation (“ODD”) to EXG110, a novel gene therapy for Fabry disease, a rare ...