Department of Immunology, Gastroenterology and Colorectal Surgery, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA Department of Medicine and The Will Rogers ...

BACKGROUND Oxidative and nitrosative stress have been implicated in the pathogenesis of inflammatory bowel diseases. AIMS To study the role of nitric oxide (NO) derived from inducible NO synthase ...

Introduction Background: Optimal patient preparation for colonoscopy is shown to improve polyp detection in the colon. In Japan, it is widely accepted practice to administer a mucolytic agent prior to ...

Dr M J A P Govers, Numico Research BV, PO Box 7005, 6700 CA Wageningen, The Netherlands. BACKGROUND Recent studies suggest that resistant starch (effective in producing butyrate and lowering possibly ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

BACKGROUND: 6-Mercaptopurine and its prodrug azathioprine are effective medications for refractory inflammatory bowel disease. However, use of these drugs has been limited by concerns about their ...

BACKGROUND Butyrate oxidation within the colonocyte is selectively inhibited by hydrogen sulphide, reproducing the metabolic lesion observed in active ulcerative colitis. AIMS To study generation of ...

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...

Objective Since the publication of the first Asia Pacific Consensus on Colorectal Cancer (CRC) in 2008, there are substantial advancements in the science and experience of implementing CRC screening.

1 Department of Immunology, Pole of Biology, Hôpital Archet 1, CHU de Nice, Université de Nice Sophia-Antipolis, Nice, France 2 EA 6203, Université de Nice Sophia Antipolis Nice, Nice, France 3 ...

Correspondence to: Professor J Dent Department of Gastroenterology, Hepatology, and General Medicine, Level 7, North Wing, North Terrace, Royal Adelaide Hospital ...

Background: Prophylactic efficacy against colitis following lactobacillus consumption in interleukin 10 (IL-10) knockout (KO) mice has been reported. Whether this applies equally to other probiotic ...