Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic fibrosis (CF) lung disease. Despite this, no CF-specific anti-inflammatory ...

Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...

Interstitial Lung Disease Center, Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center and University of Colorado Health Sciences Center, Denver, ...

BACKGROUND An obstructive defect is usual in bronchiectasis, but the pathophysiological basis of airflow obstruction remains uncertain. High resolution computed tomographic (CT) scanning now allows ...

2 Pediatric Respiratory and Allergy Units, “Arrixaca” University Children's Hospital, University of Murcia and CIBER of Epidemiology and Public Health (CIBERSP), Murcia, Spain 3 Division of Community ...

1 Department of Respiratory and Sleep Medicine, John Hunter Hospital and Hunter Medical Research Institute, University of Newcastle, NSW 2310, Australia 2 Mothers and Babies Research Centre, Hunter ...

1 Department of Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio, USA Background The mechanisms underlying chronic obstructive ...

Background Newborn bloodspot screening (NBS) for cystic fibrosis (CF) was introduced across the UK in 2007 but the impact on clinical outcomes and health inequalities for children with CF is unclear.

1 Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, P O Box 913, Dunedin, New Zealand 2 Department of Paediatric Respiratory Medicine, Erasmus MC - Sophia ...

Background The Global Obstructive Lung Disease (GOLD) 2011 revision recommends the multidimensional assessment of COPD including comorbidities and has developed a ...

Otago and Canterbury Respiratory Research Groups, Dunedin and Christchurch Schools of Medicine, University of Otago Medical School, New Zealand Dr D R Taylor, Department of Medicine, Dunedin School of ...

Objective We assessed associations between physical activity and lung function, and its decline, in the prospective population-based European Community Respiratory Health Survey cohort.