Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic fibrosis (CF) lung disease. Despite this, no CF-specific anti-inflammatory ...

Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...

Interstitial Lung Disease Center, Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center and University of Colorado Health Sciences Center, Denver, ...

1 Respiratory Medicine, Royal Infirmary of Edinburgh and University of Edinburgh, Edinburgh, UK 2 Department of Respiratory Medicine, University Hospitals Birmingham NHS Foundation Trust (Queen ...

2 Pediatric Respiratory and Allergy Units, “Arrixaca” University Children's Hospital, University of Murcia and CIBER of Epidemiology and Public Health (CIBERSP), Murcia, Spain 3 Division of Community ...

Correspondence to Michael A Mitchell, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; MichaelA.Mitchell{at}lhsc.on.ca Background Pleural ...

1 Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan 2 Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, ...

BACKGROUND An obstructive defect is usual in bronchiectasis, but the pathophysiological basis of airflow obstruction remains uncertain. High resolution computed tomographic (CT) scanning now allows ...

Background Severe obesity causes respiratory morbidity and mortality. The impact of obesity on the mechanics of breathing is not fully understood. Conclusions Obese subjects have markedly increased ...

Epidemiology Unit, Tuberculosis Research Centre, Chennai, Indian Council of Medical Research, India Correspondence to: Dr C Kolappan, Epidemiology Unit, Tuberculosis Research Centre, Mayor V R ...

1 Department of Radiology, NHO Kinki-Chuo Chest Medical Center, Sakai City, Osaka, Japan 2 Department of Internal Medicine, NHO Kinki-Chuo Chest Medical Center, Sakai City, Osaka, Japan Correspondence ...

Background Newborn bloodspot screening (NBS) for cystic fibrosis (CF) was introduced across the UK in 2007 but the impact on clinical outcomes and health inequalities for children with CF is unclear.