Novo Nordisk today announced interim results from the phase 3 FRONTIER3 trial of 70 children (aged 1-11 years old) with haemophilia A with and without inhibitors. The trial initially assessed ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Percutaneous coronary intervention administration of statins enhances the ...

This bridging replaces factor VIII, restoring thrombin production and clotting ability. The open-label, 2-part phase 3 FRONTIER3 trial (ClinicalTrials.gov Identifier: NCT05306418), evaluated the ...

Properties of the formed thrombus may influence thrombolysis efficiency and impede recanalization success. Here we examine whether differences thrombin generation are associated with unfavourable ...

Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-5127, United States ...