In addition, α-lactalbumin acquires tumoricidal activity after partial unfolding and binding to oleic acid. The lipid cofactor serves the dual role as a stabilizer of the altered fold of the ...

In in vitro analyses we dissected the synergism of CTX and TAMs and found that macrophages exposed to CTX switched to a proinflammatory phenotype and became tumoricidal by a TAM-autonomous and T-cell ...

which in turn have tumoricidal effects. Cyclophosphamide, a DNA-alkylating agent, induces non-apoptotic cell death of tumour cells and T cells. In addition, it can deplete regulatory T cells ...

These anti-inflammatory proteins hamper the activity of tumoricidal immune cells while simultaneously potentiating tumour cell metastasis. Created with BioRender.com. 4 Targeting the cGAS/STING ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

Table 1 Antibody-mediated and genetic depletion models for the in vivo study of basophils in different pathological conditions. The authors also evaluated the cytokines produced in the heart 3 days ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

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