Kangpu Biopharmaceuticals, Ltd. ('Kangpu') today announced that the Company has received IND approval from the CDE (Center ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS) in regulating the tumor microenvironment (TME) and driving cancer progression. The study ...

One of the first things that students learn when they enter a biology class is the central dogma: DNA → RNA → ...

Researchers developed a cancer vaccine that uses tumor lysate to enhance immune recognition of solid tumors. The vaccine ...

E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

A growing body of research suggests that infections, including those caused by common bacteria in gum disease, could ...

Ubiquitin-specific protease 7 (USP7) is involved in DNA repair and cell cycle progression and, due to its control over the ubiquitination of key proteins, may impact oncogenes like MDM2 and c-Myc, as ...

Researchers have developed a cancer vaccine method that can target virtually any solid tumor, amplifying the visibility of ...

Beijing Earthwise Technology Co. Ltd. has synthesized E3 ubiquitin-protein ligase CBL-B inhibitors reported to be useful for the treatment of cancer.

The concept of using vaccines to treat cancers has been around for several decades. A vaccine was first approved for prostate ...