New research has detailed how UNC45, a protein chaperone, distinguishes between healthy and faulty myosin in muscle cells, ...

Scientists at Inventisbio Co. Ltd. and Inventisbio LLC have divulged E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.

A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed ...

As the global population ages, the importance of understanding neurological disorders increases exponentially. Two ...

Nimbus Saturn Inc. has identified proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase-binding moiety covalently linked to a mitogen-activated protein kinase kinase kinase kinase ...

James Desmet explores Targeted Protein Degradation, a potential drug discovery strategy capable of treating previously ...

Discover how targeting E3-X ligase could revolutionize SLE treatment by enhancing anti-inflammatory effects while reducing ...

News 2023; News 2022; News 2021; News 2020; News 2019; News 2018; News 2017; 2024 graduation ceremony and Biology Section awards. The award ceremony to ...

在大脑的神秘世界中，神经干细胞（Neural Stem Cells, NSC）的静息和增殖之间的微妙平衡至关重要。这种平衡不仅影响成人神经发生和体内平衡，还决定了大脑能否有效地修复和再生。小的泛素相关修饰物（SUMO, Small Ubiquitin ...