综合这项研究的结论和讨论部分来看，研究人员发现巨噬细胞是肾钙化中肌成纤维细胞的重要来源，参与了 CaOx 诱导的纤维化过程。EZH2 是促进肾纤维化的关键调节因子，它通过抑制 Dusp23 的表达，导致 SMAD3 在 Ser423/425 位点磷酸化，从而促进 MMT 过程，加重肾纤维化。而抑制 EZH2，无论是通过基因敲除还是药物抑制，都能减轻 MMT ...

Experiencing a kidney stone often means enduring sharp, intense pain in the back, side, or lower abdomen, which may radiate towards the groin. This pain is typically caused by a small, hard mineral ...

The short answer is yes, orange juice is high in vitamins and minerals. But it can become less nutritious with lots of added ...

Discover how acetaminophen use during pregnancy may elevate ADHD risk in children. Learn about the implications of prenatal ...

An Instagram reel claims that bay leaves water with apple cider vinegar eliminates gall stones and kidney stones in 3 days. The claim by the user is FALSE.ClaimIn an Instagram reel it is ...

To investigate the long-term impact of superselective renal artery embolization (SRAE) on renal function in cases of severe post-percutaneous nephrolithotomy (PCNL) haemorrhage, and to identify the ...

J Midwifery Womens Health. 2008;53(2):115-122. The mechanisms of action for sterile water injections are not fully clear, but the Gate Control Theory is one logical explanation. This theory was ...

一项发表于Urolithiasis的研究[8]对13例肾结石患者与13例正常人的粪便菌群进行比较，发现结石患者与健康人群的肠道菌群在丰度和多样性上存在明显 ...