2023). During infection, EBOV proteins such as VP40 and GP, along with the viral genome, localize to TNTs containing F-actin and tubulin. Intriguingly, EBOV nucleocapsids can induce the formation of ...

Spir proteins nucleate actin polymerization by assembling a linear actin oligomer along a cluster of four actin-binding WH2 domains, and this process is enhanced by formins of the Cappuccino family.

This study provides important insights into how IL-1 cytokines protect cells against SARS-CoV-2 infection. By inducing a non-canonical RhoA/ROCK signaling pathway, IL-1beta inhibits the ability of ...

The study by Pudlowski et al. shows that a previously-identified protein complex, composed of delta- and epsilon-tubulin together with TEDC1 and TEDC2, functions in generating centriolar triplet ...

ThermoScientific SuperSignal chemiluminescent substrate was required to visualize HELZ2, SP1, and Na+/K+ ATPase. For actin, tubulin, and histone H3, standard ThermoScientific ECL substrate was used.

Currently known maternal genetic variants explain only a limited number of cases. Variants of the β-tubulin subunit gene, TUBB8, cause oocyte meiotic arrest and RPEA through a broad spectrum of ...

Influx of leukocytes at sites of inflammation is a hallmark of many diseases. Local factors released during tissue damage or cellular stress called ‚alarmins‘ promote leukocyte recruitment and ...

Yansong conducts interdisciplinary research on molecular condensation in signal transductions and actin remodeling during plant immunity and fungal polarity. Yansong did his Ph.D. at The Chinese ...