2023). During infection, EBOV proteins such as VP40 and GP, along with the viral genome, localize to TNTs containing F-actin and tubulin. Intriguingly, EBOV nucleocapsids can induce the formation of ...

Currently known maternal genetic variants explain only a limited number of cases. Variants of the β-tubulin subunit gene, TUBB8, cause oocyte meiotic arrest and RPEA through a broad spectrum of ...

In contrast with multiciliated cells, zeta-tubulin in cycling cells does not localize to centrioles and instead is associated with the TRiC-CCT complex, a large cytoplasmic chaperone that is ...

The coordination between actin and microtubule network is crucial, yet this remains a challenging problem to dissect and our understanding of the underlying mechanisms remains limited. In this study, ...

Actin has well established functions in cellular morphogenesis. However, it is not well understood how the various actin assemblies in a cell are kept in a dynamic equilibrium, in particular when ...

Actin filaments assemble inside the nucleus in response to multiple cellular perturbations, including heat shock, protein misfolding, integrin engagement, and serum stimulation. We find that DNA ...