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解码乳腺癌 “暗物质”:转座子如何重塑转录组并开启诊疗新方向?
在神秘的生命科学领域,基因组就像一本记录着生命奥秘的天书,而转座子(Transposable elements,TEs)则是其中充满 “变数” 的特殊篇章。TEs 在人类基因组中占据着约一半的 “领地”,别看它们大多因为积累了突变或者受到宿主的抑制机制,失去了 “跳跃”(转座)的能力,但这些 “安静” 下来的 TEs ...
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