Introduction Angioedema is a well-known side effect of treatment with an angiotensin-converting enzyme (ACE) inhibitor and one that we have been willing to accept in view of the incidence of the ...

as “the putative mediator of angioedema induced by ACE inhibitors”. LCZ696 was designed to overcome the problem of angioedema. “Drugs that concurrently inhibit neprilysin and block ...

There remains an art as much as a science to the use of these drugs. The science behind ACE inhibitor use is well accepted, the art, however, is a work in progress, with many subtleties to use ...

Angiotensin II blocking drugs do not affect bradykinin levels and thus do not induce angioedema and cough to the same extent as ACE inhibitors. The first and second generation calcium channel ...

Medically reviewed by Christopher Lee, MD Congestive heart failure (CHF), sometimes simply called heart failure, happens when ...

History of ACEI-associated or other angioedema. Anuria. Sulfonamide allergy. Concomitant neprilysin inhibitors (eg, sacubitril); do not administer benazepril/HCT within 36hrs of switching to or ...