Here we discuss natural and engineered structural modifications of IgG antibodies that can impact the interactions with complement, FcγRs, FcRn and resulting downstream effector functions. The two ...

Researchers from the University of Pittsburgh and NIH developed a broadly neutralizing antibody that protects monkeys from severe H5N1 avian flu by targeting a stable region of the virus, reducing the ...

They are a type of medical treatment. Scientists make monoclonal antibodies, or mAbs, in a lab. They work like the natural antibodies your body makes to fight illness. They go out into your body ...

You can get in touch with Ian by emailing [email protected]. Languages: English. Antibody-based immune therapy could become a key weapon in the fight against bird flu after trials in monkeys ...

The antibody targets a stable part of the bird flu virus, ensuring that the immune protection can resist new variants and offer long-term protection against the globally spreading airborne infection.

An antibody molecule consists of two heavy chains (approximately 50 kDa each) and two light chains (approximately 25 kDa each). These chains are interconnected by disulfide bonds, resulting in a ...

Numerous enveloped viruses, such as coronaviruses, influenza, and respiratory syncytial virus (RSV), utilize class I fusion proteins for cell entry. During this process, the proteins transition from a ...