Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense ...
9 小时
Pharmaceutical Technology on MSNEli Lilly pays $10m upfront for Organovo’s FXR agonistEli Lilly (Lilly) has agreed to make a $10m upfront payment for full worldwide rights to San Diego-based Organovo Holdings’ ...
2 天
News Medical on MSNConsiderations for taking ASO discovery programs into animal modelsStrong evidence for ALS often comes from familial forms of the disease, where specific gene mutations— for example in the ...
Cure Rare Disease has been awarded a $5.69 million grant from the California Institute for Regenerative Medicine (CIRM) to advance the development of an antisense oligonucleotide therapy for ...
In this study, we tested if locked nucleic acid (LNA) miR-181a-5p antisense oligonucleotides (ASO) could be used as a therapeutic to limit articular cartilage degeneration. Methods We used a variety ...
Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have ...
7 天
GlobalData on MSNBiogen and Stoke Therapeutics to commercialise Dravet syndrome treatmentBiogen has entered a collaboration with Stoke Therapeutics to develop and and commercialise zorevunersen to treat Dravet ...
5 天
News Medical on MSNNeurofilament light as a translational biomarker from preclinical drug discovery to ...Neurofilament light (NFL) is a powerful and sensitive biomarker for tracking neuronal health and disease progression.
2 天
Medpage Today on MSNApixaban Has Edge Over Other OACs for Older HIV Patients With AfibWarfarin was associated with more risk than apixaban (Eliquis; 55.38 vs 21.42 per 1,000 person-years, HR 2.60, 95% CI ...
20 小时
Stockhead on MSNHealth Check: What’s up, Doc? Not much – post Covid patients are still avoiding GP visitsOne of Australia's biggest pathology providers reports that GP visits and pathology volumes remain well below the historical ...
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